HIV Gene Therapy

Suppression of HIV in Gene-Modified Lymphocytes

Published in AIDS Weekly, September 30th, 1996

Gene-modified lymphocytes can be rendered less susceptible to HIV replication, Duke University research Magnus Gottfredsson and colleagues report.

This applies to T-cell lines and preliminary results indicate that some protection may also be achieved in gene-modified T cells from uninfected individuals. Further studies clearly need to be performed to confirm these observations.

The potential value of using gene-modified T lymphocytes to suppress HIV replication is currently being studied by several investigators in the US and Europe. For the past years researchers at Duke University, Durham, North Carolina, funded by the NIH have studied several...

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Source: AIDS Weekly (1996-09-30)

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