HIV Gene Therapy

Designer Protein Combats HIV Replication

Published in AIDS Weekly, October 28th, 1996

An experimental and unique method of blocking HIV replication may lead to a class of drugs that fight the virus.

The technique, which has so far been tested only in cultured human cells, relies on gene therapy with a non-working virus protein to "vaccinate" HIV infection-prone cells, according to a report in the October 15, 1996, issue of the Proceedings of the National Academy of Science (Proceedings of the National Academy of Sciences 1996;93:11477-11481).

"[Drug] combination therapy is the direction people are going in and this could be another form of combination therapy when used in conjunction with protease inhibitors," said Dr. Charles Craik,...

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Source: AIDS Weekly (1996-10-28)

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