Pathogenesis (HIV)
Approach Described for Monitoring HIV
Published in AIDS Weekly, November 4th, 1996
A group of Italian investigators has suggested a way to monitor the rate of apoptosis, based on serum levels of epsilon (gamma-gultamyl) lysine isodipeptide. "Previous studies have shown "tissue" transglutaminase (tTG) to be an important element of the cell death program," explained Dr. Mauro Piacentini, Universtia di Roma, Italy (Prod Natl Acad Sci USA 1996;93:11057-11062). Piacentini and colleagues also found high levels of tTG in peripheral blood mononuclear cells and lymphoid tissues of HIV positive subjects, compared with HIV negative...
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Source: AIDS Weekly (1996-11-04)
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