AIDS Pathogenesis

Do Progesterone Contraceptives Increase AIDS Risk?

Published in AIDS Weekly, November 18th, 1996

Progesterone implants increased vaginal simian immunodeficiency virus (SIV) transmission nearly eight fold in female monkeys.

Several of the progesterone-treated animals also appeared to have accelerated progression of SIV disease compared to untreated controls.

"This study shows that SIV genital infection and disease course are enhanced by subcutaneous implants containing progesterone when compared to the rate of vaginal transmission in the follicular phase," wrote Preston A. Marx of the Aaron Diamond AIDS Research Center and his colleagues.

Marx et al. reported their findings in the journal Nature Medicine ("Progesterone...

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Source: AIDS Weekly (1996-11-18)

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