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Transmission (Vertical)

"Mother-to-Infant Transmission of Human Immunodeficiency Virus Type 1 Involving Five Envelope Sequence Subtypes."

Published in AIDS Weekly, February 24th, 1997

According to the authors' abstract of an article published in Journal of Virology, "Genetic analysis of human immunodeficiency virus type 1 (HIV-1) from cases of mother-to-infant transmission were analyzed in an effort to provide insights into the viral selection that may occur during transmission, as well as the timing and source of transmitted viruses. HIV-1 env genes obtained from seven mothers and their perinatally infected infants in Sweden were studied. Five envelope sequence clades (A to E) were found to be represented. We used a heteroduplex tracking assay (HTA) to assess the genetic relatedness between early viral isolates from the infants and serial maternal virus populations...

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