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Vertical Transmission (Antiviral Therapy)

"Intrapartum Zidovudine (ZDV) Infusion Alone Failed to Reduce Maternal HIV-1 Viremia and Vertical Transmission in HIV-1 Infected Pregnant Women with No Prior Antenatal Care."

Published in AIDS Weekly, February 24th, 1997

According to an abstract submitted by the authors to the 3rd International Congress on Drug Therapy in HIV Infection, held November 3-7, 1996, in Birmingham, United Kingdom, "Purpose of the study: In Thailand, the risk of vertical transmission of HIV-1 infection is approximately 24-42%. However, a significant number which is up to 30% of HIV-1 infected pregnant women walked in for delivery without previous antenatal care (ANC). Thus, the ACTG 076 ZDV treatment regimen could not be implemented in these individuals. An alternative regimen warrants for investigation. This study is to determine the role of intrapartum ZDV infusion alone in reduction of maternal HIV-1 viral load...

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