Conference Coverage (Retrovirus)

HIV Ig Safe In Ugandan Women and Infants

Published in AIDS Weekly, March 10th, 1997

Anti-HIV hyperimmune serum is safe and may be effective in preventing mother-to-child HIV transmission in Africa.

Preliminary results from a Phase I/II trial show that a Ugandan HIV immunoglobulin (Ig) product had no serious toxicity after a single infusion given to mothers at 37-38 weeks' gestation and to infants within their first 16 hours of life.

None of the first eight infants to reach six weeks of age has any sign of HIV infection as tested by polymerase chain reaction (PCR) assay and/or virus culture.

J.B. Jackson of Johns Hopkins University, Baltimore, Maryland, reported the findings at the Fourth Conference on...

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Source: AIDS Weekly (1997-03-10)

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