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Genetic Analysis (HIV-1)

"Positive and Negative Sense Transcription from the HIV-1 LTR."

Published in AIDS Weekly, March 17th, 1997

According to an abstract submitted by the authors to the 8th Annual Conference of the Australasian Society for HIV Medicine, in association with the Three National Centres in HIV Research, and the Australian and New Zealand Association of Nurses in AIDS Care, and the Social Workers in AIDS, held November 14-17, 1996, in Sydney, Australia, "HIV-1 gene expression is regulated by cellular proteins which bind to sites in the U3 region of the long terminal repeat (LTR). We have analyzed interactions with sequences upstream of the core enhancer, which is well characterized. Wild type and mutant synthetic oligonucleotides based on HIV-1HXB2, and nuclear protein extracts derived from various...

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