"Potential Molecular Genetic Interventions for AIDS."

According to an abstract submitted by the authors to the 3rd Conference on Retroviruses and Opportunistic Infections, held January 28 - February 1, 1997, in Washington, DC, "Since the acquired immunodeficiency syndrome (AIDS) has been refractory to traditional pharmacologic interventions, alternative approaches have been developed. For example, gene products can be introduced in vivo to confer protection against HIV infection by stimulation of the immune system or by preventing infection of otherwise susceptible cells. We have described methods to stimulate immune responses in vivo, and a human gene therapy protocol is being performed to assess the safety and toxicity of gene transfer...

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