Virology

Mechanism Identified By Which T Cells Resist Infection by HIV-1

Published in AIDS Weekly, May 5th, 1997

A technique for growing CD4⁺ T cells renders them resistant to HIV-1 infection by preventing the expression of a recently discovered coreceptor essential for HIV-1 infection.

A collaborative team of virologists and immunologists from the Walter Reed Army Institute of Research, the U.S. National Institutes of Health (NIH), the Naval Medical Research Institute, and the Henry M. Jackson Foundation for the Advancement of Military Medicine, led by Carl June, M.D., presented their findings in the April 11, 1997, issue of Science

They had previously discovered that triggering the CD28 receptor on CD4⁺ T cells promoted vigorous cell...

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Source: AIDS Weekly (1997-05-05)

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