Conference Coverage (NCVDG)

HIV's Hidden Epitopes Now a Tempting Vaccine Target

Published in AIDS Weekly, May 19th, 1997

A new vaccine strategy would force HIV to expose crucial epitopes normally hidden from the immune system.

The strategy, still on the drawing board, is based on new insights into HIV gained from the identification of cellular chemokine receptors as necessary for HIV infectivity.

Harvard researcher Craig Gerard described these studies - and their implications for vaccine strategies - in a plenary presentation to the 9th Annual Meeting of the National Cooperative Vaccine Development Groups for AIDS (NCVDG), held May 4-7, 1997, in Bethesda, Maryland.

Gerard suggested that HIV fuses to cells only after a two-step process. In step one,...

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Source: AIDS Weekly (1997-05-19)

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