Published in AIDS Weekly, June 2nd, 1997
The remarkable finding offers hope for a safe, attenuated AIDS vaccine using the goat virus or a genetically engineered variant carrying HIV genes. It is strikingly reminiscent of the earliest vaccine: Edward Jenner's discovery that a relatively harmless cow virus (cowpox or vaccinia) could protect humans against smallpox.
The goat virus is caprine arthritis-encephalitis virus (CAEV).
"A major obstacle to designing live attenuated vaccines using primate lentiviruses is the substantial health threat to humans," noted Angeline Douvas of the...
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