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New Antibody Protects Against HIV Even After Exposure

Published in AIDS Weekly, June 2nd, 1997

A novel monoclonal antibody (MAb) protects animals from HIV or SIV infection even when given after challenge with infectious virus.

The MAb, dubbed B4, was developed by United Biomedical Inc. (UBI), Hauppage, New York.

If B4 works in humans, it could be used as a "morning-after" drug to prevent HIV infection after exposure to the virus. A vaccine that stimulated B4-like antibodies could also be developed.

"B4, in humanized form, is a promising candidate for use in post-exposure prophylaxis," said Carl V. Hanson of the California Department of Health Services, Berkeley, California. "A new approach to HIV vaccine...

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