Published in AIDS Weekly, June 9th, 1997
"ISIS 5320 is a phosphorothioate oligonucleotide which binds to the V3 loop of the viral envelope protein gp120, preventing fusion of HIV to the cellular CD4 receptor," explained researcher Karen Schwikart, of the U.S. National Cancer Institute, Bethesda, Maryland at the conference. "It is active against HIV-1 and HIV-2 isolates, including clinical strains."
Schwikart's group conducted...
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