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PET Images Track HIV Spread

Published in AIDS Weekly, June 9th, 1997

Positron emission tomography (PET) can be used to monitor progression of HIV disease and to assess protection by antiviral drugs and/or vaccines.

The technique, developed by C. David Pauza and colleagues at the University of Wisconsin, Madison, uses radiolabelled fluorodeoxyglucose (FDG) to mark tissues with the highest metabolic activity. PET scans can then provide three-dimensional images of these tissues.

"FDG/PET provides a noninvasive method for assessing the effects of HIV infection on lymphoid tissue activation and can be used to characterize early pathways for virus dissemination, to monitor disease progression, or to evaluate the protective...

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