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Transient HIV Infection In Adults: Genetic Resistance?

Published in AIDS Weekly, June 9th, 1997

People infected with an HIV strain to which they happen to be genetically resistant can, in some cases, eradicate the virus.

Elucidation of the mechanism of this resistance is of enormous interest to AIDS vaccine researchers, who are still attempting to define the elusive correlates of immunity to HIV.

Miles W. Cloyd and colleagues of the University of Texas Medical Branch, Galveston, reported in 1991 that CD4+ T lymphocytes vary in their susceptibility to different strains of HIV-1 (Cloyd et al., Virology, 184(2):723-8). As members of the same family tended to have the same resistance patterns, Cloyd et al. suggested that...

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