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Conference Coverage (SPIRAT/NCDDG-HIV)

New HIV Trick: Beginning Replication Outside of Cells

Published in AIDS Weekly, July 14th, 1997

HIV can begin its replication process before entering cells, permitting it to infect quiescent cells previously thought to be virus resistant.

"HIV virions can be able, in the correct extracellular milieu, to reverse transcribe its RNA to DNA," said Roger J. Pomerantz of the Center for Human Virology at Thomas Jefferson University, Philadelphia, Pennsylvania.

Pomerantz announced the findings in a presentation to "New Opportunities for HIV Therapy - From Discovery to Clinical Proof-of-Concept," the 2nd Joint Conference of the National Institute of Allergy and Infectious Diseases (NIAID) Strategic Program for Innovative Research on AIDS Treatment...

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