AIDS Pathogenesis
HIV Can't Directly Kill Enough T Cells To Cause AIDS
Published in AIDS Weekly, September 1st, 1997
A study of tonsil biopsies from people at various stages of HIV disease show that depletion of CD4+ T cells occurs when viral load reaches a threshold level in lymphoid tissue.
"At a threshold level when only about 1:100 tonsillar CD4+ T cells are infected, and only approximately 3:10,000 tonsillar T cells are active virus producers, the balance between tonsillar CD4 cells lost and replaced is disturbed and the level of tonsillar CD4+ T cells starts to fall," reported Bard Rosok of the Center for Research in Virology, Bergen,...
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Source: AIDS Weekly (1997-09-01)
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