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Kaposi's sarcoma (KSHV)

"Ultrastructural Characterization of Human Herpesvirus 8 (Kaposi's sarcoma-Associated Herpesvirus) in Kaposi's sarcoma Lesions: Electron Microscopy Permits Distinction from Cytom

Published in AIDS Weekly, September 15th, 1997

According to the authors' abstract of an article published in Journal of Pathology, "Kaposi's sarcoma (KS) has been shown by molecular techniques to be associated with infection with human herpesvirus 8 (HHV8/KSHV), but specific ultrastructural characterization of the virus has been impaired by the frequent presence in these lesions of other herpesviruses, particularly cytomegalovirus (CMV). Since the ultrastructural appearance of HHV8/KSHV has been studied in the cell line KS-1 uninfected with other viruses including CMV, it was possible to undertake a comparative study of CMV and HHV8/KSHV in KS lesions. KHV8/KSHV was sparsely present and lytic infection was restricted to endothelial...

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