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Transmission (HIV)

"Biological Correlates of HIV-1 Heterosexual Transmission."

Published in AIDS Weekly, September 15th, 1997

According to the authors' abstract of an article published in AIDS, "Objectives: To study the role of HIV-1 biological phenotype, viral load and neutralizing antibodies in male-to-female heterosexual transmission of HIV-1. Methods: Seven transmitting and seven non-transmitting HIV-1-seropositive heterosexual male index cases were included in the present study. All couples had engaged in unprotected sex for a period of over 1 year. Transmission was defined by the seroconversion of the female sexual partner. Virus isolates were tested in MT-2 cells for replication and syncytia induction. HIV-1 RNA plasma load was measured by the branched DNA technique. Serum...

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