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Blood Banking (Storage)

Optimal Conditions Assure Detection of p24 Antigen

Published in AIDS Weekly, September 22nd, 1997

Blood samples undergoing HIV p24 antigen testing require special storage conditions.

Optimal conditions include storage at 4(degree) C before freezing and long-term storage at -70(degree) C, said Max Arens, Washington University School of Medicine, St. Louis, Missouri, and colleagues ("Stabilities of Free and Complexed Human Immunodeficiency Virus p24 Antigens during Short- and Long-Term Storage," Journal of Clinical Microbiology, September 1997;35:2413-2416).

Arens et al. found that in using the standard p24 assay, a 25 to 27 percent decrease in free p24 antigen in serum occurred after storage at 4(degree) C over 14 days, however; there was no loss...

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