AIDS Therapies (Fortovase)

New Saquinavir Formulation Said to be Better than Invirase

Published in AIDS Weekly, September 29th, 1997

A formulation of saquinavir, one of the protease inhibitor drugs that have helped revolutionize AIDS treatment, gives a stronger response than its older drug Invirase, the manufacturer, Hoffmann-La Roche, said.

The soft-gel formulation, to be marketed as Fortovase, gave 10 times the exposure that current, hard-gel version of Invirase gives, Roche said in a statement. When given in triple-combination therapy, the drug helped lower blood levels of HIV to below detectable limits, scientists working with Roche told a meeting of the Infectious Disease Society of America.

They said they gave Fortovase along with the more standard drugs AZT and 3TC to 41...

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Source: AIDS Weekly (1997-09-29)

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