"The Structure and Coding Organization of the Genomic Termini of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8)."

According to the authors' abstract of an article published in Virology, "Kaposi's sarcoma-associated herpesvirus (KSHV) is a novel human herpesvirus closely linked to two AIDS-related neoplasms. We have prepared DNA from KSHV virions produced in cell culture and have examined the structure of the viral genomic termini. As in the related simian herpesvirus H. saimiri (HVS), the central unique region of KSHV DNA is bounded by tandemly repeated units of noncoding, GC-rich DNA. The KSHV repeats are 803 bp in length and are 85% G+C. Each molecule harbors 35-45 such repeats, but the repeats are not arrayed uniformly and symmetrically at each end. Rather, different molecules appear to...

Want to see the full article?

• Purchase this article for only $3.00