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Blood Banking (Screening)

Anti-HBc Is Not Cost Effective for Preventing Transfusion-Transmitted HIV

Published in AIDS Weekly, November 24th, 1997

Screening blood donors for antibody to hepatitis B core antigen (anti-HBc) is an ineffective way to detect HIV infected units of blood.

"The low yield and very poor cost-effectiveness of anti-HBc screening indicate that this test is not an effective screening test for HIV-1 WP [window period] donations," wrote Michael P. Busch, M.D., Ph.D., University of California, San Francisco, and Irwin Memorial Blood Centers, San Francisco, California, and colleagues ("Value and Cost-Effectiveness of Screening Blood Donors for Antibody to Hepatitis B Core Antigen As a Way of Detecting Window-Phase Human Immunodeficiency Virus Type 1 Infections," Transfusion, October...

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