Conference Coverage (Retrovirus)
New Canarypox Vaccine Elicits Durable Anti-HIV CTLs
Published in AIDS Weekly, March 9th, 1998
Results from a Phase II clinical trial point to a positive answer.
The trial investigated the ability of Pasteur Merieux/Connaught's new canarypox-based HIV vaccine - given alone or in various combinations with Chiron's rgp120 SF2 HIV peptide vaccine - to evoke HIV specific CD8+ CTL responses.
"A strategy of inclusion of multiple [HIV] genes into a canarypox vector given with rgp120 SF2 results in neutralizing antibodies and broad and durable CD8+ CTL," reported T.G. Evans of the University of Rochester,...
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Source: AIDS Weekly (1998-03-09)
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