Kaposi's Sarcoma
"Randomized Comparative Trial of Pegylated Liposomal Doxorubicin Versus Bleomycin and Vincristine in the Treatment of AIDS-Related Kaposi's Sarcoma."
Published in AIDS Weekly, March 30th, 1998
According to the authors' abstract of an article published in Journal of Clinical Oncology, "Purpose: Cytotoxic chemotherapy is frequently required for the more severe manifestations of human immunodeficiency virus (HIV) related Kaposi's sarcoma. Combinations of bleomycin and vincristine (BV) or BV with the addition of doxorubicin (ABV) are the most commonly used regimens against which new treatments may be compared. We report a multicenter Phase III study that compared pegylated liposomal doxorubicin (PLD) to the BV combination. Patients and Methods: We conducted a randomized study that compared PLD 20 mg/m2 with a combination of bleomycin 15...
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Source: AIDS Weekly (1998-03-30)
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