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AIDS Therapies

Undetectable HIV: Big Gap Between <20 and <400 Copies

Published in AIDS Weekly, March 30th, 1998

Highly active antiretroviral therapy (HAART) is truly successful only when it reduces plasma HIV RNA levels to less than 20 copies/mL.

The results come from a very small study over the course of only one year. They require verification in studies with larger numbers of patients carried out over longer periods of time.

"These findings argue that HIV replication differs significantly between patients on potent antiretroviral therapy with plasma RNA levels of <20 copies/mL, those with 20 to 400 copies/mL, and those with >400 copies/mL," wrote University of San Diego researchers Huldrych F. Gunthard, Douglas D. Richman, and colleagues.

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