Hematopoietic Stem Cells
HIV-2 Does Not Infect Most-Primitive Progenitor Cells
Published in AIDS Weekly, April 6th, 1998
"Our results show that HIV-2, similar to HIV-1, does not infect hematopoietic stem cells in vitro with any significant frequency and infected cells are not present in LTCICs [long-term culture-initiating cells]," wrote University of Maryland researcher Frank F. Weichold, and colleagues ("Neither Human Immunodeficiency Virus-1 (HIV-1) Nor HIV-2 Infects Most-Primitive Human Hematopoietic Stem Cells As Assessed in Long-Term Bone Marrow Cultures," Blood, 1998;91:907-915).
The authors said their findings may have important implications for therapeutic strategies, such as those...
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Source: AIDS Weekly (1998-04-06)
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