Published in AIDS Weekly, August 10th, 1998
The AIDS virus docks to susceptible cells via specific chemokine receptors. Since chemokines act as cellular messengers that tell T cells when and where to go, it is possible that HIV binding itself sends a message affecting T-cell trafficking.
Claudia Cicala and colleagues at Anthony Fauci's National Institutes of Health laboratory discovered that this is exactly the case.
"HIV may recruit uninfected target cells to areas with high concentration of virus such as lymphoid tissue," Cicala said in a presentation to the 12th World...
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