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Dual Infection (HCV/TB)

Treatment-Related Liver Toxicity Worse in HCV Positive Patients

Published in AIDS Weekly, August 24th, 1998

Hepatitis C virus infection appears to play an important role in the development of treatment-induced liver problems in tuberculosis patients.

"Considering the potential large number of patients infected with both TB and hepatitis C virus (HCV) who may need (antituberculosis therapy), this association may have important implications," Jaime R. Ungo and colleagues wrote ("Antituberculosis Drug-Induced Hepatotoxicity, The Role of Hepatitis C Virus and HIV," American Journal of Respiratory and Critical Care Medicine, July, 1998;157:1871-1876).

"Clinicians treating patients at high risk for HIV and/or HCV with anti-TB agents may need to consider...

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