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Conference Coverage (12th World AIDS)

Healthy Epithelia Impervious To HIV

Published in AIDS Weekly, September 21st, 1998

Sexual transmission of HIV appears possible only when the cells lining body cavities are disturbed, a CDC study suggests.

The in vitro findings suggest that HIV can't penetrate normal mucosal epithelial barriers. They focus attention on factors - such as sexually transmitted diseases (STDs) - that may help the virus enter the body.

"These findings lead us to a clearer understanding of factors influencing the sexual transmission of HIV," said Charlene Dezzutti of the U.S. Centers for Disease Control and Prevention (CDC), Atlanta, Georgia. "This is the first study to demonstrate that normally functioning epithelial cells are incapable of transmitting...

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