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Immunology

Robust Response Mounted vs. Opportunistic Infection After Aggressive HIV Therapy

Published in AIDS Weekly, September 21st, 1998

University of California San Francisco (UCSF) researchers reported results that suggest the immune system of HIV patients mounts a robust response to at least one opportunistic infection following aggressive HIV drug therapy.

The finding, reported in the August 1998 issue of Nature Medicine, focused specifically on cytomegalovirus (CMV), the leading cause of blindness in people with AIDS. But the researchers said the study may help to clarify an ongoing question in HIV treatment: Do the CD4+ T cells that are replenished by the immune system after highly active antiretroviral therapy (HAART) create the pathogen-specific responses needed to combat the...

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