AIDS Vaccines
Whether Live Vaccine Saves or Kills Up To Host Factors
Published in AIDS Weekly, September 28th, 1998
The finding comes from the most extensive study to date of rhesus monkeys given a prototype live, attenuated AIDS vaccine (SIVmac239 delta nef) and then challenged with pathogenic virus (SIVmac251).
Aaron Diamond AIDS Research Center researchers Ruth I. Connor and colleagues collected data on not only on the animals' immune responses but also on both vaccine-virus and challenge-virus dynamics over time.
Among the study's provocative findings is the suggestion that host factors, already known to affect the permissiveness of an...
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Source: AIDS Weekly (1998-09-28)
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