Published in AIDS Weekly, October 5th, 1998
"The characterization of the Tat-induced signal transduction pathway in KS may provide insights into developing targeted therapies to inhibit its growth and spread," wrote Ramesh K. Ganju, Harvard Institutes of Medicine, and colleagues ("Human Immunodeficiency Virus Tat Modulates the Flk-1/KDR Receptor, Mitogen-Activated Protein Kinases, and Components of Focal Adhesion in Kaposi's Sarcoma Cells," Journal of Virology, 1998;72:6131-6137).
KS spindle cell growth and spread have been reported to be modulated by various cytokines as...
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