Published in AIDS Weekly, December 14th, 1998
Several genetic variants have been found to offer various degrees of protection against AIDS. New findings by National Cancer Institute researchers Maureen P. Martin and colleagues are the first to identify an AIDS-accelerating gene.
The recessive gene is expressed as a variant of the CCR5 chemokine receptor, the key used by macrophage-tropic HIV strains in the vast majority of infections. In order to have increased susceptibility to AIDS a person must inherit the gene, called CCR5P1, from both parents. Unfortunately, this happens quite often.
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