Published in AIDS Weekly, December 28th, 1998
Human herpes virus 8 (HHV-8) or Kaposi's sarcoma-associated herpes virus (KSHV), is a gamma herpes virus with sequence homology to Epstein-Barr virus (EBV). HHV-8 was first isolated from Kaposi's sarcoma tumor cells and subsequently from tumor cells and peripheral blood mononuclear cells from patients with primary effusion lymphomas (PEL; or body cavity-based lymphomas).
PEL has been recognized as an individual nosologic entity based on its distinctive biological-pathological features and its consistent infection with HHV-8 (commonly, but not...
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