Opportunistic Infections

Early Results: Successful HAART Can End PCP Prophylaxis

Published in AIDS Weekly, February 1st, 1999

New findings suggest that people aggressively treating their HIV infections can take one fewer pill.

The most deadly opportunistic infection among western AIDS patients is Pneumocystis carinii pneumonia (PCP). Trimethoprim-sulfamethoxazole (TMP/SMX; cotrimoxazole) is the drug combination of choice for PCP prevention. It is recommended for all HIV infected patients when their T-cell counts fall below 200 cells/(mu)L.

But can PCP prophylaxis be discontinued when T cell counts rise above 200 cells/(mu)L in patients receiving highly active antiretroviral therapy (HAART) regimens' The cautious answer, based on early follow-up data, is yes.

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Source: AIDS Weekly (1999-02-01)

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