"Effect of Change from TID to BID Nelfinavir (NFV) on Viral Load and CD4 Count."

According to an abstract submitted by the authors to the International Conference on the Discovery and Clinical Development of Antiretroviral Therapies, held December 13-17, 1998, in St. Thomas, West Indies, US Virgin Islands, "Trials of NFV 1250 mg BID compared to 750 mg TID in ARV-naive persons with HIV infection have shown comparable antiretroviral effect and tolerability. No study has looked at the effect of switching from TID to BID dosing in treatment-experienced persons. Methods: We reviewed the records of all HIV infected patients (N=14) who had been switched from TID to BID dosing. All were on 3 drug therapy including NFV. Results: Participants included 12...

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