"Viability and Recovery of Peripheral Blood Mononuclear Cells Cryopreserved for Up to 12 Years in a Multicenter Study."

According to the authors' abstract of an article published in Clinical and Diagnostic Laboratory Immunology, "The Multicenter ATDS Cohort Study (MACS), an ongoing prospective study of the natural history of human immunodeficiency virus (HIV), has stored biologic specimens, including peripheral blood mononuclear cells (PBMC), from 5,622 participants for up to 12 years. The purpose of the present analysis was to evaluate the quality of the PBMC in the MACS repository in order to test the validity and feasibility of nested retrospective studies and to guide the planning of future repositories. PBMC were collected from MACS participants at four centers at six-month intervals from 1984 to...

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