Drug Development (Antivirals)
"Nucleosides With Dual AntiHIV and HBV Activity."
Published in AIDS Weekly, March 1st, 1999
NIH Grant Number: 5ROIA141980-02. Grant Expires: July 31, 2000. Principle Investigator: Raymond F. Schinazi. Performing Organization: Emory University, Atlanta, Georgia. Description: The overall goal of this Interactive Research Project Grant (IRPG) is to develop new antiviral nucleosides, for use in combination against human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections. As a first step, the applicant wishes to focus on a new compound discovered in his laboratory that has dual potent and selective activity against HIV/HBV. b-D-2,'3'-Didehydro-2',3-dideoxy-5-fluorocytidine (D-D4FC) and related molecules will be...
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Source: AIDS Weekly (1999-03-01)
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