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Conference Coverage (Retrovirus)

AIDS Vaccine From Mutant-Fingered HIV?

Published in AIDS Weekly, March 1st, 1999

Could DNA encoding HIV with mutant zinc fingers work as an AIDS vaccine'

Yes, according to monkey studies conducted at the U.S. National Cancer Institute (NCI).

Three of four animals that received the prototype vaccine remain AIDS free four to five years after challenge with pathogenic simian immunodeficiency virus (SIV).

"We created a particle that can't package its RNA," said Larry O. Arthur, director of the AIDS Vaccine Program at the NCI-Frederick Cancer Research and Development Center (NCI-FCRDC), Frederick, Maryland.

Arthur spoke in a poster discussion session at the 6th Conference on Retroviruses and...

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