AIDS Immunotherapy

Adoptively Transferred T Cells Die a Rapid Death

Published in AIDS Weekly, March 22nd, 1999

The failure of adoptive transfer of T cells in AIDS patients is caused by rapid apoptosis of the infused cells.

Rusung Tan and colleagues from several institutions in Oxford, United Kingdom, investigated the fate of expanded HIV specific cytotoxic T lymphocyte (CTL) clones in vivo following adoptive transfer to a patient with AIDS ("Rapid Death of Adoptively Transferred T Cells in Acquired Immunodeficiency Syndrome," Blood, March 1, 1999;93(5):1506-10).

"HIV specific CTL probably play the major role in controlling HIV replication," wrote Tan et al. "However, the value of adoptive transfer of HIV specific CTL expanded in vitro to HIV⁺...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of AIDS Weekly

Source: AIDS Weekly (1999-03-22)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry