Published in AIDS Weekly, March 22nd, 1999
Rusung Tan and colleagues from several institutions in Oxford, United Kingdom, investigated the fate of expanded HIV specific cytotoxic T lymphocyte (CTL) clones in vivo following adoptive transfer to a patient with AIDS ("Rapid Death of Adoptively Transferred T Cells in Acquired Immunodeficiency Syndrome," Blood, March 1, 1999;93(5):1506-10).
"HIV specific CTL probably play the major role in controlling HIV replication," wrote Tan et al. "However, the value of adoptive transfer of HIV specific CTL expanded in vitro to HIV+...
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