Pharmacokinetics

Indinavir Dosing Shouldn't Be Dependent on Codosing with Nevirapine

Published in AIDS Weekly, April 19th, 1999

A pharmacokinetic study examining the interaction between indinavir and nevirapine suggests that indinavir dosing should be dependent on drug exposure.

Nevirapine and indinavir have the potential to affect each other's pharmacokinetics.

In a prospective trial, 24 HIV infected subjects on stable nucleoside or no therapy were treated with 800 mg of indinavir every eight hours ("Antiviral Effect and Pharmacokinetic Interaction between Nevirapine and Indinavir in Persons Infected with HIV Type 1," Journal of Infectious Disease, May 1999;179(5):1116-1123).

After seven days, 200 mg of nevirapine a day was added for 14 days and then...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of AIDS Weekly

Source: AIDS Weekly (1999-04-19)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry