Conference Coverage

Nobel Laureate Foresees CMI Vaccines

Published in AIDS Weekly, April 19th, 1999

Vaccines that elicit cell mediated immunity (CMI) are on the way, predicted 1996 Nobel Prize winner Peter C. Doherty.

Doherty and colleague Rolf M. Zinkernagel jointly won medicine's top honor for their discovery that CMI responses are triggered by the T-cell recognition of foreign antigens in the context of the "self" molecules now known as major histocompatibility complex (MHC) antigens. They published the key findings of this work in 1974 (Nature, 1974;248:701-2 and Nature, 1974;251:547-8).

Now affiliated with St. Jude Children's Research Hospital, Memphis, Tennessee, Doherty is working with murine gamma-herpesvirus 68 (MHV-68). This virus...

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Source: AIDS Weekly (1999-04-19)

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