Published in AIDS Weekly, May 17th, 1999
The product is the small (11 kDa) protein cyanovirin-N (CV-N). It was originally isolated at the U.S. National Institutes of Health (NIH) from the cyanobacterium Nostoc ellipsosporum during a search for natural products with anti-HIV activity.
Without loss of antiviral activity, CV-N can resist physiochemical degradation. It can withstand treatment with denaturants, detergents, organic solvents, multiple cycles of freezing and thawing, and heat up to 100(degree)C.
CV-N is known to target the HIV gp120 envelope...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.