Published in AIDS Weekly, June 14th, 1999
TP is one of the major hematopoietic defects seen in patients with HIV infection. It often occurs in the context of bone-marrow invasion by neoplasms or opportunistic infections, but some HIV infected patients develop TP of unknown etiology.
Frosso Voulgaropoulou of Washington University, St. Louis, Missouri, and colleagues now show that HIV strains with the syncytium-inducing (SI) phenotype can be isolated from the bone marrow of HIV infected patients with TP. These strains differ significantly from those isolated from patients with TP of known etiology.
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