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HAART

"Effects of Antiretroviral Therapy on Immune Reconstitution."

Published in AIDS Weekly, August 30th, 1999

According to an abstract submitted by the authors to the 10th Symposium on HIV Infection, held June 17-19, 1999, in Toulon, France, "Highly active antiretroviral therapy in established disease has proven to be efficient at restoring, at least partially, CD4 T-cell homeostasis and responses to opportunistic pathogens. The CD4 T-cell responses against HIV are, however, not restored except at time of primary infection, and currently represent a new surrogate marker for immune reconstitution. We evaluated the parameters influencing the long-term recovery in CD4 T cells and in CD4 cell reactivity to HIV after 2-3 years of HAART. The magnitude of long-term viral load reduction was the major...

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