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Tat Toxoid Immunogenic, Safe In Human Trials

Published in AIDS Weekly, September 13th, 1999

A new AIDS vaccine/treatment strategy is moving quickly through human trials.

The immunogen is an inactivated form of the HIV Tat protein. It could be both a vaccine and a treatment for AIDS.

"We have carried out three clinical trials in humans," reported A. Gringeri of IRCCS Maggiore Hospital, Milan, Italy, in a presentation to the 1999 Meeting of the Institute of Human Virology, held August 28-September 2 in Baltimore, Maryland.

Tat toxoid is being developed and tested in a collaboration between Robert Gallo and colleagues of the Institute of Human Virology and Daniel Zagury, Gringeri, and colleagues at IRCCS. C. David Pauza...

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