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SQ IL-2 + HAART: The Key to HIV Control?

Published in AIDS Weekly, October 18th, 1999

Interleukin 2 (IL-2) may be the push the immune system needs to roll over HIV.

When given together with highly active antiretroviral therapy (HAART), daily subcutaneous (SQ) IL-2 boosts T-cell and natural-killer (NK) cell counts, a new study confirms. Even more exciting are data suggesting that IL-2 given in this context can restore lost immunity to HIV to the degree that a patient could stop taking HAART and avoid the drugs' side effects.

E.L. Jacobson and colleagues of Cornell University, New York, set up a protocol in which patients added SQ IL-2 to their HAART regimens. Some of the patients are scheduled to stop taking HAART when their T-cell...

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