AIDS Therapies (Animal Models)

Model Suggests AIDS Drugs May Not Abolish HIV Infection

Published in AIDS Weekly, October 18th, 1999

Current AIDS drugs may never eradicate HIV from infected individuals, according to a model of the decline in HIV levels during treatment.

Rather, antiretroviral treatment drives HIV down to stable levels, which vary with the efficacy of the drug regimen.

One implication of the new model could be a more favorable interpretation of some treatment outcomes once described as failures, according to a report in the October 1999 issue of Nature Medicine.

"Our interpretation is fundamentally different than the currently accepted one," said William E. Paul, MD, chief of the Laboratory of Immunology at the U.S. National Institute of...

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Source: AIDS Weekly (1999-10-18)

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